Sepsis Research Today is a free monthly online journal that collates and summarizes the latest research about Sepsis, including details on septicemia, diagnosis, symptoms, treatment.

Looking for the target cell of Kaposi's sarcoma-associated herpesvirus.

Dupin N, Grange PA

Service de Dermatologie, Hôpital Cochin, Laboratoire de Recherche en Dermatologie, Unité UPRES1833, Faculté de Médecine Paris V, Université René Descartes, Paris, France. nicolas.dupin@cch.ap-hop-paris.fr

The level of Kaposi's sarcoma-associated herpesvirus (KSHV) cellular viremia in patients with Kaposi's sarcoma could be related to both the tumor burden and its progression. The origin of the spindle cell, the hallmark cell of Kaposi's sarcoma, is still debated. Two hypotheses may be formulated, favoring a lymphatic endothelial cell or an endothelial-cell precursor evolving into a lymphatic phenotype, both preferentially targeted by KSHV.

Published 16 February 2006 in J Invest Dermatol, 126(3): 545-7.
Full-text of this article is available online (may require subscription).

© 2004-2008 Sepsis Research Today. All Rights Reserved.