Sepsis Research Today is a free monthly online journal that collates and summarizes the latest research about Sepsis, including details on septicemia, diagnosis, symptoms, treatment.

Taurolidine lock: the key to prevention of recurrent catheter-related bloodstream infections.

Jurewitsch B, Jeejeebhoy KN

Digestive Diseases Program, St. Michael's Hospital, University of Toronto, 30 Bond St., Toronto, Ont., Canada M5B 1W8. jurewitschb@smh.toronto.on.ca

The literature shows that repeated courses of antibiotics and catheter removals in a subset of patients suffering from multiple catheter-related bloodstream infections (CRBSI), are unlikely to prevent recurrence. In acceding to preventative strategies, we report our application of the antimicrobial chemotherapeutic Taurolidine used as a daily flush solution in seven home TPN patients suffering from multiple episodes. A pretreatment infection rate of 10.8 infections per 1000 catheter days decreased to 0.8 after treatment.

Published 17 May 2005 in Clin Nutr, 24(3): 462-5.
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