Sepsis Research Today is a free monthly online journal that collates and summarizes the latest research about Sepsis, including details on septicemia, diagnosis, symptoms, treatment.

Drotrecogin alpha (activated) in neonatal septic shock.

Frommhold D, Birle A, Linderkamp O, Zilow E, Pöschl J

Division of Neonatology, Department of Paediatrics, University of Heidelberg Medical School, Heidelberg, Germany. david_frommhold@med.uni-heidelberg.de

A 12-d-old neonate suffering from group B streptococcal septic shock was treated with 24 microg/kg/h recombinant human activated protein C [rhAPC, drotrecogin alpha (activated)] for 96 h. The protein C activity increased from 5% to 53% after rhAPC infusion. The patient recovered within 14 d without any adverse effects.

Published 4 April 2005 in Scand J Infect Dis, 37(4): 306-8.
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